Dental ozone is a safe and natural therapy that utilizes ozone gas for various dental applications. Ozone, composed of three oxygen molecules, is a powerful oxidizing agent with antimicrobial and healing properties. Ozone can be used in water, gas, or oil. When applied in dentistry, ozone gas can provide antimicrobial action, minimally invasive treatment, enhanced healing and regeneration, reduced sensitivity and discomfort, and biocompatibility.